Allantoin has been classified by the Food and Drug Administration (FDA) Over-the-Counter (OTC) Topical Analgesic Review Panel as a Category I (safe and effective) active ingredient skin protectant when used at 2.0%. Allantoin has been widely used for decades in cosmetic and OTC topical formulations because it is so effective at only 0.5%, making it an economical anti-inflammatory additive. The most popular applications are in the prevention and treatment of dry and chapped skin and lips.
Allantoin is also used in the topical pharmaceutical market in psoriasis medications and analgesic gels. Allantoin has been used in various dental preparations such as toothpastes and oral rinses.
Allantoin produces its desirable effects by promoting healthy skin. It is postulated that Allantoin cleanses away necrotic tissue, speeding up the growth of new, healthy tissue. Since Allantoin stimulates new and healthy tissue growth, healing epithelization may take place. Allantoin also has been described as a cell proliferant, an epithelization stimulant and a chemical debrider in texts such as the United States Dispensatory, Merck Index, and British Pharmaceutical Codex. Allantoin is an amphoteric compound that is anionic under basic conditions. Allantoin is compatible with most ingredients used in personal care formulations.
SPECIFICATIONS
- white free flowing powder
- water soluble - 1g to 199ml
- store tightly closed and away from direct heat and moisture
- 36 mos. when stored properly
USAGE GUIDELINES
- * add to room temperature, 76F, water phase, then heat to 130F to ensure solubilization
- 0.5 to 2.0%
- Hand and body creams and lotions
- Lipsticks and lip ointments
- Shaving products
- Sun and after-sun care products
- Face and baby wipes
- Baby and foot powders
- Acne products
- Anti-perspirants and deodorants
- Diaper rash creams
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